THIS TRIAL HAS NOW CLOSED.
Stem cell transplant (also known as a bone marrow transplant) is an upcoming treatment for sickle cell disorders and is a potential cure. However, it is only available through the NHS to those with severe sickle cell disorders who have a sibling who does not have sickle cell disease and is a full match.
The REDRESS study has been set up to find out whether haplo-identical (half-matched) transplants are safe and effective in people with sickle cell disorders. This involves having stem cells donated from a close relative (such as a parent or a sibling who is not a full match). This kind of transplant is commonly performed in other patient groups, but more information is needed in people with sickle cell disorders before this can be approved by the NHS.
We hosted a virtual patient information evening on stem cell transplant in sickle cell disorders on Tuesday, February 18th 2025 with the team who are running the REDRESS trial. It was great to hear more about the trial and how stem cell transplant is being used for people with sickle cell disorders.
Anthony Nolan have put together a resource for people with sickle cell disorders who are considering a stem cell transplant as a potential treatment option. Visit their page for more information: Sickle cell disease (SCD) and stem cell transplant | Anthony Nolan
Or for more information on the REDRESS study, visit: redresstrial.co.uk
